SCHEMBL573719

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6912401	0.90	GABRA1 (0.47)	GABRA1GABRB2TSHRHTR1ADRD2
	SCHEMBL7605260	0.83	GABRA1 (0.40)	GABRA1GABRB2TSHRHTR1ADRD2
	SCHEMBL2200675	0.83	GABRA1 (0.55)	GABRA1GABRB2HTR1ADRD2DRD4
	SCHEMBL631373	0.83	TSHR (0.46)	GABRA1GABRB2TSHRHTR1AIAPP
	SCHEMBL27588717	0.82	TSHR (0.50)	GABRA1GABRB2TSHRIAPPHSPA5
	SCHEMBL9816664	0.81	HSPA5 (0.56)	TSHRHSPA5CA1CA2ESR1
	SCHEMBL574234	0.79	BID (0.50)	TSHRIAPP
	SCHEMBL286832	0.79	TSHR (0.52)	TSHRHSPA5CA1CA2ESR1
	Nitrogen SCHEMBL10979594	0.78	GABRA1 (0.50)	GABRA1GABRB2HTR1ADRD2DRD4
	SCHEMBL573936	0.78	BID (0.57)	TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.