Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrogen SCHEMBL10979594 | 0.95 | GABRA1 (0.50) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL7788783 | 0.90 | GABRA1 (0.48) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL16950743 | 0.88 | GABRA1 (0.50) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL17450488 | 0.88 | GABRA1 (0.44) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL91279 | 0.87 | PNMT (0.62) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL3781759 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL6829666 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL11637531 | 0.84 | GABRA1 (0.46) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL16959855 | 0.83 | GABRA1 (0.45) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL573719 | 0.83 | GABRA1 (0.56) | GABRA1GABRB2HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1409699-A | Process for preparation of secondary and tertiary amines | CELGRO (US) | 2003-04-09 | — | — | CN | claimed |
| EP-1237844-A1 | PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINES | Celgro (US) | 2002-09-11 | — | — | EP | claimed |
| WO-2001044162-A1 | PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINES | CELGRO (US) | 2001-06-21 | — | — | WO | claimed |
| US-6107521-A | Process for the preparation of secondary amines | CELGRO (US) | 2000-08-22 | — | — | US | claimed |
| CN-110305171-B | Preparation and application of mixed nickel (II) complex containing bisoxazoline-derived nitrogen heterocyclic carbene ligand and phosphite ligand | 苏州大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-110305171-A | The preparation and application of mixed matching nickel (II) complex containing nitrogen heterocycle carbine ligand derived from double oxazolines and phosphite ester ligand | 苏州大学 | 2019-10-08 | — | — | CN | disclosed |
| CN-109422680-A | A kind of synthetic method of N- acetylquinoline -2- amide and its derivative | 浙江工业大学 | 2019-03-05 | — | — | CN | disclosed |
| CN-108299622-A | For improving polyurethane（PU）The method of the hydrolytic resistance of matrix system | 朗盛德国有限责任公司 | 2018-07-20 | — | — | CN | disclosed |
| CN-106146829-B | A kind of polymer containing two or more pyrenyl groups and its production and use | 烟台大学 | 2018-01-30 | — | — | CN | disclosed |
| US-20110230680-A1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-09-22 | — | — | US | disclosed |
| US-7977286-B2 | Substituted N,N'-diaryl-m-phenylenediamines impart good levels of oxidation inhibition in lubricants, hydraulic fluids; lubricant is a synthetic oil derived from a Fischer-Tropsch wax via palladium/phosphine complex coupling catalyst; engine, industrial, marine, hydraulic, aviation, driveline oils | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-07-12 | — | — | US | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-2029706-A2 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | ExxonMobil Research and Engineering Company (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007133462-A2 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-22 | — | — | WO | disclosed |
| US-20070265178-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2007-11-15 | — | — | US | disclosed |
| CN-1409699-A | Process for preparation of secondary and tertiary amines | CELGRO (US) | 2003-04-09 | — | — | CN | disclosed |
| US-6107521-A | Process for the preparation of secondary amines | CELGRO (US) | 2000-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | GABRA1 991/4885GABRB2 561/4885HTR1A 3657/4885 |
| US-20070265178-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | GPX4, SOD1, GPX1 | GABRA1 4834/4885GABRB2 4822/4885HTR1A 3291/4885 |
| US-20110230680-A1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | GPX4, SOD1, GPX1 | GABRA1 4828/4885GABRB2 4817/4885HTR1A 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.