Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737475 | 0.88 | GPR35 (0.46) | ALDH1A1HPGDCYP11B1CYP11B2MEN1 | |
| SCHEMBL5738434 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL5699201 | 0.75 | ALDH1A1 (0.54) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL4591881 | 0.73 | ALDH1A1 (0.57) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL30590644 | 0.72 | ALDH1A1 (0.49) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL4881892 | 0.72 | ALDH1A1 (0.60) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL11300000 | 0.71 | ALDH1A1 (0.65) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL5738353 | 0.69 | ALDH1A1 (0.42) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL30590650 | 0.68 | MMP2 (0.49) | ALDH1A1CYP1A2HPGDCYP2C19MMP2 | |
| SCHEMBL5206974 | 0.67 | ALDH1A1 (0.54) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |