Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654399 | 0.77 | DNM1 (0.41) | DNM1CA2MAPK1CA1ALDH1A1 | |
| SCHEMBL18812607 | 0.71 | FDPS (0.41) | DNM1CA2MAPK1CA1ALDH1A1 | |
| SCHEMBL11496837 | 0.69 | CA2 (0.42) | DNM1CA2MAPK1CA1ALDH1A1 | |
| SCHEMBL597711 | 0.69 | DNM1 (0.39) | DNM1CA2MAPK1CA1ALDH1A1 | |
| SCHEMBL7928844 | 0.69 | OPRM1 (0.43) | DNM1CA2TSHRFDPSLMNA | |
| SCHEMBL13016812 | 0.69 | DNM1 (0.35) | DNM1CA2MAPK1CA1ALDH1A1 | |
| SCHEMBL29690364 | 0.67 | CA2 (0.33) | DNM1CA2MAPK1CA1ALDH1A1 | |
| SCHEMBL6383487 | 0.67 | CA2 (0.33) | DNM1CA2MAPK1CA1ALDH1A1 | |
| SCHEMBL4609939 | 0.67 | CA2 (0.38) | DNM1CA2MAPK1CA1ALDH1A1 | |
| SCHEMBL23641692 | 0.67 | FDPS (0.39) | DNM1CA2MAPK1CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680218-A2 | SINGLE COMPONENT CATIONIC PALLADIUM PROINITIATORS FOR THE LATENT POLYMERIZATION OF CYCLOOLEFINS | Promerus, LLC (US) | 2006-07-19 | — | — | EP | claimed |
| WO-2005042147-A2 | SINGLE COMPONENT CATIONIC PALLADIUM PROINITIATORS FOR THE LATENT POLYMERIZATION OF CYCLOOLEFINS | PROMERUS, LLC (US) | 2005-05-12 | — | — | WO | claimed |