Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532762 | 0.82 | CYP19A1 (0.48) | RXRARXRBRXRGCYP19A1CYP11B1 | |
| SCHEMBL5735902 | 0.80 | BRD4 (0.48) | HDAC6SMN1; SMN2MAOBMAPTMAOA | |
| SCHEMBL6675702 | 0.79 | CYP2C9 (0.43) | RXRARXRBRXRGCYP19A1SMPD1 | |
| SCHEMBL656838 | 0.77 | MRGPRX4 (0.50) | RXRARXRBRXRGCYP19A1CYP11B1 | |
| SCHEMBL448625 | 0.76 | RXRA (0.59) | RXRARXRBRXRGL3MBTL1MAPT | |
| SCHEMBL8028726 | 0.75 | CYP19A1 (0.52) | RXRARXRBRXRGCYP19A1CYP11B1 | |
| SCHEMBL19404699 | 0.75 | ALOX5AP (0.61) | RXRARXRBRXRGCYP19A1CYP11B1 | |
| SCHEMBL2062891 | 0.74 | SMPD1 (0.56) | CYP19A1SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL5659691 | 0.73 | MAOB (0.58) | CYP19A1CYP11B1CYP11B2RAB9ASMN1; SMN2 | |
| SCHEMBL1316136 | 0.73 | HPGD (0.51) | CYP19A1FOLH1SMPD1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549309-A4 | SOMATOSTATIN ANALOGUE COMPOUNDS | CHEMBRIDGE RES LAB INC (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1549309-A2 | SOMATOSTATIN ANALOGUE COMPOUNDS | ChemBridge Research Laboratories, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2003090677-A2 | SOMATOSTATIN ANALOGUE COMPOUNDS | CHEMBRIDGE RESEARCH LAB., LLC (US) | 2003-11-06 | — | — | WO | disclosed |