Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16491109 | 0.89 | FFAR4 (0.54) | HPGDLMNAEGFRERBB2ALDH1A1 | |
| SCHEMBL15534823 | 0.87 | HTT (0.57) | FOLH1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL24767093 | 0.86 | LMNA (0.46) | HPGDLMNAEGFRERBB2KDM4E | |
| SCHEMBL11563262 | 0.84 | MAOB (0.56) | HPGDLMNAFOLH1KDM4EALDH1A1 | |
| SCHEMBL4416634 | 0.84 | FOLH1 (0.58) | HPGDLMNAFOLH1KDM4EALDH1A1 | |
| SCHEMBL11565369 | 0.84 | LRRK2 (0.59) | HPGDLMNAFOLH1KDM4EALDH1A1 | |
| SCHEMBL6564646 | 0.84 | RXRA (0.47) | HPGDLMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6566658 | 0.84 | PDK2 (0.49) | HPGDKDM4EALDH1A1HTTGAA | |
| SCHEMBL5431545 | 0.83 | LRRK2 (0.63) | HPGDLMNAFOLH1KDM4EALDH1A1 | |
| SCHEMBL6680832 | 0.83 | HPGD (0.51) | HPGDLMNAFOLH1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604322-A1 | LACTULOSE GLYCOSIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | FRUITHY HOLDINGS LIMITED (CN) | 2020-02-05 | — | — | EP | disclosed |
| US-9603852-B2 | Treatment of obesity and pulmonary arterial hypertension | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-9603852-B2 | Treatment of obesity and pulmonary arterial hypertension | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| WO-2017025849-A1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS | PFIZER INC. (US) | 2017-02-16 | — | — | WO | disclosed |
| US-20160113933-A1 | TREATMENT OF OBESITY AND PULMONARY ARTERIAL HYPERTENSION | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2016-04-28 | — | — | US | disclosed |
| US-8952150-B2 | Prostaglandin transporter inhibitors and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| CN-102333757-B | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2014-11-26 | — | — | CN | disclosed |
| US-8492582-B2 | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2013-07-23 | — | — | US | disclosed |
| CN-102333757-A | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2012-01-25 | — | — | CN | disclosed |
| US-20110275797-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-11-10 | — | — | US | disclosed |
| EP-2385036-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275797-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | COL14A1, COL2A1, COL1A1 | HPGD 1236/4885LMNA 546/4885FOLH1 3884/4885 |
| US-20160113933-A1 | TREATMENT OF OBESITY AND PULMONARY ARTERIAL HYPERTENSION | PTGIR, PTGIS, FABP4 | HPGD 182/4885LMNA 2014/4885FOLH1 394/4885 |
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | HPGD 557/4885LMNA 4043/4885FOLH1 3685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.