Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 3/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14898019 | 0.92 | MAPT (0.54) | MAPTTSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL1955176 | 0.85 | MAPT (0.62) | MAPTTSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL30771563 | 0.84 | NPC1 (0.61) | MAPTTSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL6509573 | 0.84 | GRM5 (0.53) | MAPTTSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL2152084 | 0.84 | NPC1 (0.61) | MAPTTSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL8306382 | 0.84 | MAPT (0.50) | MAPTTSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL1498503 | 0.83 | MAPT (0.53) | MAPTTSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL6465956 | 0.83 | NPY2R (0.54) | MAPTTSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL8309661 | 0.82 | MAPT (0.48) | MAPTTSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL14861923 | 0.82 | NPC1 (0.49) | MAPTTSHRNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660488-A1 | NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS | Warner-Lambert Company LLC (US) | 2006-05-31 | — | — | EP | disclosed |
| US-20050131229-A1 | Production method of 2,6-dihalopurine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-06-16 | — | — | US | disclosed |
| US-20050065187-A1 | Novel antimicrobial aryloxazolidinone compounds | GORDEEV MIKHAIL FEDOROVICH (US) | 2005-03-24 | — | — | US | disclosed |
| WO-2005019214-A1 | NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131229-A1 | Production method of 2,6-dihalopurine | TPMT, DHPS, DUS2 | MAPT 1574/4885TSHR 1641/4885NPC1 3031/4885 |
| US-20050065187-A1 | Novel antimicrobial aryloxazolidinone compounds | XDH, NQO1, MPO | MAPT 4849/4885TSHR 4071/4885NPC1 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.