Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638697 | 0.84 | SRC (0.60) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL6055394 | 0.84 | PDE5A (0.46) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL11138508 | 0.83 | LMNA (0.59) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL19578003 | 0.83 | TRPA1 (0.50) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Potassium SCHEMBL29477955 | 0.83 | SRC (0.59) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL29477949 | 0.83 | SRC (0.59) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| Thymol SCHEMBL27973976 | 0.80 | LMNA (0.78) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL9768521 | 0.79 | PDE5A (0.52) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL30893084 | 0.79 | SRC (0.59) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL16071368 | 0.79 | PDE5A (0.51) | TRPA1LMNACHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017204-A1 | EFFICIENT AND COST-EFFECTIVE PROCESS FOR THE MANUFACTURE OF AMYL M-CRESOL | AESICA PHARMACEUTICALS LIMITED (GB) | 2012-02-09 | — | — | WO | disclosed |