Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 8/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741464 | 1.00 | SLC6A9 (0.43) | SLC6A9OPRM1SLC6A5OPRL1CAMK2A | |
| SCHEMBL5363402 | 0.84 | SLC6A9 (0.53) | SLC6A9OPRM1SLC6A5OPRL1CAMK2A | |
| SCHEMBL1689596 | 0.84 | SLC6A9 (0.53) | SLC6A9OPRM1SLC6A5OPRL1CAMK2A | |
| SCHEMBL5740969 | 0.80 | SLC6A9 (0.54) | SLC6A9OPRM1SLC6A5OPRL1CAMK2A | |
| SCHEMBL5740972 | 0.80 | SLC6A9 (0.54) | SLC6A9OPRM1SLC6A5OPRL1CAMK2A | |
| SCHEMBL5741677 | 0.79 | SLC6A9 (0.43) | SLC6A9OPRM1SLC6A5OPRL1KMT2A | |
| SCHEMBL5741682 | 0.79 | SLC6A9 (0.43) | SLC6A9OPRM1SLC6A5OPRL1KMT2A | |
| SCHEMBL7164480 | 0.72 | ACHE (0.55) | OPRM1TSHRMAPK1KMT2AALDH1A1 | |
| SCHEMBL7252327 | 0.69 | OPRM1 (0.50) | OPRM1TSHRMAPK1KMT2AALDH1A1 | |
| SCHEMBL5363537 | 0.69 | TSHR (0.51) | SLC6A9SLC6A5CAMK2ACAMK2GTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594840-B1 | PIPERIDINE-BENZENESULFONAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-09-27 | — | — | EP | disclosed |