Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 10/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744423 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL3548483 | 0.83 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL3537491 | 0.82 | TRPV1 (0.49) | KDM4EALDH1A1MAPTSMN1; SMN2TRPV1 | |
| SCHEMBL3544303 | 0.79 | RBP4 (0.41) | KDM4EALDH1A1MAPTSMN1; SMN2RBP4 | |
| SCHEMBL3544759 | 0.78 | RBP4 (0.41) | ALDH1A1MAPTHTR1AHTR3ARBP4 | |
| Trifluoroacetic Acid SCHEMBL5742404 | 0.77 | HTR1A (0.48) | KDM4EALDH1A1MAPTSMN1; SMN2HTR1A | |
| SCHEMBL3548158 | 0.77 | MEN1 (0.42) | KDM4EALDH1A1SMN1; SMN2HTR1AHTR3A | |
| SCHEMBL3540773 | 0.77 | RBP4 (0.40) | MAPTRBP4MEN1KMT2A | |
| SCHEMBL3546222 | 0.76 | RBP4 (0.40) | ALDH1A1MAPTTRPV1RBP4MEN1 | |
| SCHEMBL3543682 | 0.75 | NPSR1 (0.36) | KDM4EALDH1A1MAPTSMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626720-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. Lundbeck A/S (DK) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004087156-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. LUNDBECK A/S (DK) | 2004-10-14 | — | — | WO | disclosed |