Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.97 |
| ▸ | GFER | P55789 | 1/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | CRHBP | P24387 | 2/20 | 0.65 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742926 | 0.84 | MAPT (0.70) | MAPTGFERKDM4ELMNATSHR | |
| Hydrochloric Acid SCHEMBL5742940 | 0.83 | MAPT (0.73) | MAPTGFERKDM4ELMNATSHR | |
| SCHEMBL5791898 | 0.82 | MAPT (0.68) | MAPTGFERKDM4ELMNATSHR | |
| SCHEMBL31647387 | 0.81 | MAPT (0.67) | MAPTGFERKDM4ELMNATSHR | |
| SCHEMBL1616232 | 0.80 | HRH4 (0.72) | MAPTGFERCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL9013259 | 0.80 | MAPT (1.00) | MAPTGFERKDM4ELMNATSHR | |
| SCHEMBL5788921 | 0.80 | CRHBP (0.96) | MAPTGFERLMNATSHRHSD17B10 | |
| SCHEMBL5742735 | 0.80 | MAPT (0.64) | MAPTGFERKDM4ELMNATSHR | |
| SCHEMBL5789932 | 0.79 | CRHBP (1.00) | MAPTGFERTSHRCRHBPCRHR2 | |
| SCHEMBL24313224 | 0.78 | CRHBP (1.00) | MAPTGFERLMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654249-A1 | ANTHELMINTIC AND INSECTICIDE PYRIMIDINE DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2006-05-10 | — | — | EP | claimed |
| WO-2006016014-A1 | NOVEL COMPOUNDS OF A 6-METHYL-PYRIMIDINE-2,4-DIAMINE FAMILY, METHOD FOR SYNTHESISING, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | L'OREAL (FR) | 2006-02-16 | — | — | WO | claimed |
| WO-2005014573-A1 | ANTHELMINTIC AND INSECTICIDE PYRIMIDINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-02-17 | — | — | WO | claimed |
| US-20050032810-A1 | Novel anthelmintic and insecticidal compositions | PHARMACIA AND UPJOHN COMPANY | 2005-02-10 | — | — | US | claimed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| EP-1654249-A1 | ANTHELMINTIC AND INSECTICIDE PYRIMIDINE DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2006016014-A1 | NOVEL COMPOUNDS OF A 6-METHYL-PYRIMIDINE-2,4-DIAMINE FAMILY, METHOD FOR SYNTHESISING, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | L'OREAL (FR) | 2006-02-16 | — | — | WO | disclosed |
| WO-2005014573-A1 | ANTHELMINTIC AND INSECTICIDE PYRIMIDINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-02-17 | — | — | WO | disclosed |
| US-20050032810-A1 | Novel anthelmintic and insecticidal compositions | PHARMACIA AND UPJOHN COMPANY | 2005-02-10 | — | — | US | disclosed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032810-A1 | Novel anthelmintic and insecticidal compositions | ACHE, DHX29, DHX35 | MAPT 3780/4885GFER 3680/4885KDM4E 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.