Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741855 | 0.87 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL5743102 | 0.84 | L3MBTL1 (0.41) | L3MBTL1MAPTDRD2DRD4DRD3 | |
| SCHEMBL3544034 | 0.84 | GPR119 (0.41) | L3MBTL1ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3546005 | 0.78 | HDAC2 (0.43) | L3MBTL1ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL5735133 | 0.78 | APP (0.45) | L3MBTL1ALDH1A1MAPTLMNAHRH2 | |
| SCHEMBL1741730 | 0.78 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL3539818 | 0.77 | GPR119 (0.40) | L3MBTL1ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3538548 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL3549234 | 0.75 | GPR119 (0.44) | L3MBTL1ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3548088 | 0.75 | MEN1 (0.43) | MAPTDRD2DRD3HRH2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626720-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. Lundbeck A/S (DK) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004087156-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. LUNDBECK A/S (DK) | 2004-10-14 | — | — | WO | disclosed |