Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735133 | 0.88 | APP (0.45) | L3MBTL1MAPTSMN1; SMN2ALDH1A1HRH2 | |
| SCHEMBL5744778 | 0.87 | L3MBTL1 (0.44) | L3MBTL1MAPTSMN1; SMN2ALDH1A1HRH2 | |
| SCHEMBL5743102 | 0.84 | L3MBTL1 (0.41) | L3MBTL1MAPTSMN1; SMN2HRH2HRH1 | |
| SCHEMBL3549538 | 0.84 | MEN1 (0.44) | L3MBTL1MAPTALDH1A1HTR1AHTR3A | |
| SCHEMBL16244844 | 0.78 | CCR1 (0.49) | SMN1; SMN2HRH1APPHTR1AOPRD1 | |
| SCHEMBL3549234 | 0.77 | GPR119 (0.44) | L3MBTL1MAPTSMN1; SMN2ALDH1A1HTR1A | |
| SCHEMBL1741730 | 0.76 | L3MBTL1 (0.53) | L3MBTL1MAPTSMN1; SMN2ALDH1A1APP | |
| SCHEMBL3547010 | 0.75 | HTR1A (0.46) | L3MBTL1MAPTSMN1; SMN2ALDH1A1HTR1A | |
| SCHEMBL5740602 | 0.75 | HTR1A (0.42) | L3MBTL1SMN1; SMN2ALDH1A1APPPSEN1 | |
| SCHEMBL7478597 | 0.74 | MEN1 (0.48) | SMN1; SMN2ALDH1A1HRH1APPHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626720-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. Lundbeck A/S (DK) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004087156-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. LUNDBECK A/S (DK) | 2004-10-14 | — | — | WO | disclosed |