SCHEMBL57450

SCHEMBL57450

COC(OC)[SiH2]CNc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
ALDH1A1 P00352 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.36
RAB9A P51151 2/20 0.36
HPGD P15428 2/20 0.36
NPC1 O15118 1/20 0.36
AGTR1 P30556 1/20 0.36
HTT P42858 2/20 0.35
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
LMNA P02545 2/20 0.34
KCNH3 Q9ULD8 1/20 0.33
TSHR P16473 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL629260 0.87 MAPT (0.36) MAPTALDH1A1SMN1; SMN2RAB9AHPGD
SCHEMBL3708781 0.81 MAPT (0.38) MAPTALDH1A1SMN1; SMN2HTTTDP1
SCHEMBL825579 0.79 MAPT (0.52) MAPTALDH1A1RAB9ANPC1L3MBTL1
SCHEMBL8466206 0.78 MAPT (0.45) MAPTALDH1A1SMN1; SMN2RAB9AHPGD
SCHEMBL29901837 0.70 ALDH1A1 (0.48) MAPTALDH1A1HTTTDP1L3MBTL1
SCHEMBL931749 0.69 MAPT (0.56) MAPTALDH1A1SMN1; SMN2RAB9AHPGD
SCHEMBL13384974 0.68 MAPT (0.39) MAPTALDH1A1SMN1; SMN2RAB9AHPGD
SCHEMBL10359187 0.67 MAPT (0.44) MAPTALDH1A1HTTTDP1L3MBTL1
SCHEMBL5076208 0.67 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2HPGDTDP1RECQL
SCHEMBL27297982 0.67 MAPT (0.40) MAPTALDH1A1HPGDHTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026041693-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-26 WO claimed
EP-4700098-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-25 EP claimed
EP-4638540-A1 A METHOD FOR PREPARING A SILANISED POLYURETHANE PREPOLYMER, ITS USE AND A METHOD FOR PRODUCING A MOISTURE-CURED SILANISED ONE-COMPONENT FOAM PCC ROKITA Spolka Akcyjna (PL) 2025-10-29 EP claimed
WO-2024136687-A1 A METHOD FOR PREPARING A SILANISED POLYURETHANE PREPOLYMER, ITS USE AND A METHOD FOR PRODUCING A MOISTURE-CURED SILANISED ONE-COMPONENT FOAM PCC ROKITA SPÓŁKA AKCYJNA (PL) 2024-06-27 WO claimed
EP-3157970-A1 SILYLATED POLYURETHANES Huntsman International LLC (US) 2017-04-26 EP claimed
WO-2015193146-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 WO claimed
US-20110198030-A1 POLYURETHANE COMPOSITION THAT CONTAINS ALPHA-SILANE AND THAT HAS ANISOTROPIC MATERIAL PROPERTIES SIKA TECHNOLOGY AG (CH) 2011-08-18 US claimed
EP-2189485-B1 Polyurethane composition comprising alpha-silane having anisostropic material properties SIKA TECHNOLOGY AG (CH) 2011-02-16 EP claimed
EP-2189485-A1 Polyurethane composition comprising alpha-silane having anisostropic material properties Sika Technology AG (CH) 2010-05-26 EP claimed
US-20260125587-A1 PROCESS FOR PRODUCING A STORAGE-STABLE ACTIVATOR FOR GLASS AND CERAMIC SUBSTRATES SIKA TECHNOLOGY AG (CH) 2026-05-07 US disclosed
WO-2026041693-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-26 WO disclosed
EP-4700098-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-25 EP disclosed
EP-4638540-A1 A METHOD FOR PREPARING A SILANISED POLYURETHANE PREPOLYMER, ITS USE AND A METHOD FOR PRODUCING A MOISTURE-CURED SILANISED ONE-COMPONENT FOAM PCC ROKITA Spolka Akcyjna (PL) 2025-10-29 EP disclosed
US-12391853-B2 Adhesive formulations for roofing applications and related methods BMIC LLC (US) 2025-08-19 US disclosed
EP-1685175-A1 POLYURETHANE COMPOSITIONS WITH NCO AND SILYL REACTIVITY Henkel Kommanditgesellschaft auf Aktien (DE) 2006-08-02 EP disclosed
US-20060148921-A1 Expansible mixtures devoid of isocyanates exhibiting improved fire behaviour WACKER CHEMIE AG (DE) 2006-07-06 US disclosed
EP-1585778-A1 HYDROPHOBIC PROPELLANT GAS MIXTURES FOR PRODUCING INSULATING FOAMS RATHOR AG (CH) 2005-10-19 EP disclosed
WO-2005049684-A1 POLYURETHANE COMPOSITIONS WITH NCO AND SILYL REACTIVITY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-06-02 WO disclosed
WO-2005019296-A1 THERMOPLASTIC POLYURETHANE CONTAINING SILANE GROUPS BASF AKTIENGESELLSCHAFT (DE) 2005-03-03 WO disclosed
WO-2004065448-A1 HYDROPHOBIC PROPELLANT GAS MIXTURES FOR PRODUCING INSULATING FOAMS RATHOR AG (CH) 2004-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125587-A1 PROCESS FOR PRODUCING A STORAGE-STABLE ACTIVATOR FOR GLASS AND CERAMIC SUBSTRATES CD40LG, CDH1, VCAM1 MAPT 498/4885ALDH1A1 435/4885SMN1; SMN2 2515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.