Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308466 | 0.90 | ALDH1A1 (0.45) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL1649 | 0.83 | CES2 (0.62) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| Hydrochloric Acid SCHEMBL630595 | 0.81 | CES2 (0.59) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL5946767 | 0.79 | PTPN1 (0.73) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| SCHEMBL101703 | 0.78 | — | — | |
| SCHEMBL2717519 | 0.77 | BCL2L1 (0.64) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| Ethylene SCHEMBL27657103 | 0.77 | CES2 (0.54) | KCNQ3KCNQ2KCNE1KCNQ1BACE1 | |
| Iodide SCHEMBL20838269 | 0.76 | TSHR (0.48) | MEN1KMT2AALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL3742607 | 0.76 | TSHR (0.48) | MAPTALDH1A1CA1CA2 | |
| SCHEMBL8700603 | 0.75 | ALDH1A1 (0.53) | HTTCES2CES1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685105-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharmaceuticals SA (CH) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005044797-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-05-19 | — | — | WO | disclosed |