SCHEMBL574612

SCHEMBL574612

Cc1cc(-c2cc(C)c(NCC(O)S(=O)(=O)O)c(C)c2)cc(C)c1NCC(O)S(=O)(=O)O

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 2/20 0.31
LMNA P02545 2/20 0.31
BLM P54132 2/20 0.31
KMT2A Q03164 2/20 0.31
APEX1 P27695 1/20 0.31
KDM4E B2RXH2 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574107 0.92 ALDH1A1 (0.41) TDP1
SCHEMBL5311847 0.80 CA1 (0.32) MAPTMAPK1TDP1L3MBTL1LMNA
SCHEMBL5313148 0.79 VDR (0.41) MEN1LMNAKMT2A
SCHEMBL574676 0.74 ALDH1A1 (0.39) TDP1
SCHEMBL574724 0.71 CDK1 (0.35) CA1CA2
SCHEMBL574593 0.69 ALDH1A1 (0.33) MAPTTDP1L3MBTL1CA1CA2
SCHEMBL574466 0.69 ALDH1A1 (0.33) MAPTTDP1L3MBTL1CA1CA2
SCHEMBL574611 0.66 ALDH1A1 (0.44) TDP1
SCHEMBL17601966 0.65 ALDH1A1 (0.42) TDP1
SCHEMBL11177788 0.64 RAPGEF4 (0.44) MAPTMAPK1TDP1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10597352-B1 Stable alkyl benzidine composition and methods of making and using same OneStep Technologies Inc. (CA) 2020-03-24 US claimed
US-4716110-A Composition for assaying hydrogen peroxide EIKEN KAGAKU KABUSHIKI KAISHA (JP) 1987-12-29 US claimed
WO-2020257930-A1 STABLE ALKYL BENZIDINE COMPOSITION AND METHODS OF MAKING AND USING SAME OneStep Technologies Inc. (CA) 2020-12-30 WO disclosed
US-10597352-B1 Stable alkyl benzidine composition and methods of making and using same OneStep Technologies Inc. (CA) 2020-03-24 US disclosed
US-9228986-B2 Simultaneous determination of multiple analytes in industrial water system GENERAL ELECTRIC COMPANY (US) 2016-01-05 US disclosed
EP-2601515-A1 SIMULTANEOUS DETERMINATION OF MULTIPLE ANALYTES IN INDUSTRIAL WATER SYSTEM General Electric Company (US) 2013-06-12 EP disclosed
US-20130122597-A1 SIMULTANEOUS DETERMINATION OF MULTIPLE ANALYTES IN INDUSTRIAL WATER SYSTEM BL TECHNOLOGIES, INC. 2013-05-16 US disclosed
WO-2012016350-A1 SIMULTANEOUS DETERMINATION OF MULTIPLE ANALYTES IN INDUSTRIAL WATER SYSTEM GENERAL ELECTRIC COMPANY (US) 2012-02-09 WO disclosed
US-20070224691-A1 Composition for measuring concentration of residual chlorine MIURA CO., LTD. 2007-09-27 US disclosed
EP-1837653-A1 Composition for measuring concentration of residual chlorine MIURA CO., LTD. (JP) 2007-09-26 EP disclosed
EP-1770394-A2 Composition for measuring residual chlorine concentration MIURA CO., LTD. (JP) 2007-04-04 EP disclosed
US-20070072305-A1 Composition for measuring residual chlorine concentration MIURA CO., LTD. 2007-03-29 US disclosed
US-4716110-A Composition for assaying hydrogen peroxide EIKEN KAGAKU KABUSHIKI KAISHA (JP) 1987-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10597352-B1 Stable alkyl benzidine composition and methods of making and using same C9, BBC3, CTRC MAPT 4307/4885MAPK1 2759/4885TDP1 3846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.