Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793022 | 0.88 | PPARG (0.48) | GSK3BPPARGLMNAHTTSMN1; SMN2 | |
| SCHEMBL5796548 | 0.86 | MCL1 (0.53) | GSK3BPPARGLMNAHTTSMN1; SMN2 | |
| SCHEMBL5746254 | 0.85 | PPARG (0.45) | PPARGTHRBCCKBRSRC | |
| Hydroxyamine SCHEMBL5793019 | 0.85 | MCL1 (0.51) | GSK3BPPARGLMNAHTTSMN1; SMN2 | |
| SCHEMBL5746821 | 0.84 | LMNA (0.53) | LMNAHTTSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL5794846 | 0.83 | PPARG (0.45) | PPARGLMNATP53MAPT | |
| SCHEMBL4972058 | 0.81 | GSK3B (0.49) | GSK3BPPARGLMNAHTTSMN1; SMN2 | |
| SCHEMBL5745384 | 0.79 | PPARG (0.49) | PPARGLMNAHTTSMN1; SMN2TP53 | |
| SCHEMBL5747678 | 0.78 | TSHR (0.49) | LMNAHTTSMN1; SMN2MAPTTSHR | |
| SCHEMBL5745589 | 0.78 | MCL1 (0.47) | GSK3BPPARGHTTSMN1; SMN2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |