Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746099 | 0.87 | GSK3B (0.46) | GSK3BTP53THRBSMN1; SMN2LMNA | |
| SCHEMBL5746821 | 0.81 | LMNA (0.53) | SMN1; SMN2LMNAHTTHDAC3HDAC4 | |
| SCHEMBL5796548 | 0.79 | MCL1 (0.53) | GSK3BTP53THRBSMN1; SMN2LMNA | |
| Hydroxyamine SCHEMBL5793019 | 0.78 | MCL1 (0.51) | GSK3BTP53THRBSMN1; SMN2LMNA | |
| SCHEMBL4972058 | 0.78 | GSK3B (0.49) | GSK3BTP53THRBSMN1; SMN2LMNA | |
| SCHEMBL5793022 | 0.77 | PPARG (0.48) | GSK3BTP53THRBSMN1; SMN2LMNA | |
| SCHEMBL5797144 | 0.75 | GSK3B (0.47) | GSK3BTP53THRBSMN1; SMN2LMNA | |
| SCHEMBL9493439 | 0.72 | GSK3B (0.55) | GSK3BTP53THRBSMN1; SMN2LMNA | |
| SCHEMBL9035893 | 0.71 | GSK3B (0.59) | GSK3BTP53THRBSMN1; SMN2LMNA | |
| SCHEMBL5746610 | 0.70 | ANPEP (0.41) | GSK3BTP53MEN1KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |