Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14762304 | 0.88 | RAB9A (0.52) | USP5RAB9ANPC1CYP2C9CYP2D6 | |
| SCHEMBL11292363 | 0.86 | CES1 (0.50) | RAB9ANPC1HIF1ASMN1; SMN2POLB | |
| SCHEMBL1409972 | 0.85 | CYP2C9 (0.49) | USP5RAB9ANPC1CYP2C9CYP2D6 | |
| SCHEMBL1618561 | 0.84 | RAB9A (0.50) | USP5RAB9ANPC1CYP2C9CYP2D6 | |
| SCHEMBL4453109 | 0.83 | USP5 (0.47) | USP5RAB9ANPC1CYP2C9CYP2D6 | |
| SCHEMBL22660971 | 0.81 | USP5 (0.46) | USP5RAB9ANPC1CYP2C9CYP2D6 | |
| Benzophenone SCHEMBL11101215 | 0.81 | ALDH1A1 (0.45) | USP5RAB9ANPC1CYP2C9CYP2D6 | |
| Benzil SCHEMBL29000475 | 0.81 | CES2 (0.48) | USP5RAB9ANPC1CYP2C9CYP2D6 | |
| SCHEMBL11889616 | 0.79 | USP5 (0.42) | USP5RAB9ANPC1CYP2C9CYP2D6 | |
| SCHEMBL5705634 | 0.78 | THRA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1729043-A1 | Gasket integrated with cover | BRIDGESTONE CORPORATION (JP) | 2006-12-06 | — | — | EP | disclosed |
| EP-0239641-A1 | DI(METH)ACRYLIC ESTERS AND RESIN COMPOSITION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-10-07 | — | — | EP | disclosed |