Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219754 | 0.81 | LMNA (0.43) | CASP3TRPV3KCNH2 | |
| SCHEMBL18068205 | 0.80 | PTGES (0.31) | — | |
| SCHEMBL7015467 | 0.76 | NPC1 (0.40) | PIK3CAKCNH2 | |
| SCHEMBL2763495 | 0.75 | NPC1 (0.45) | MAP4K4 | |
| SCHEMBL5484106 | 0.73 | CASP3 (0.48) | CASP3TRPV4PIK3CAPI4KBPIK3CD | |
| SCHEMBL13841426 | 0.72 | LMNA (0.55) | — | |
| SCHEMBL26848732 | 0.72 | PIK3CA (0.43) | CASP3TRPV3TRPV4PIK3CAPI4KB | |
| SCHEMBL14488216 | 0.71 | CASP3 (0.52) | CASP3TRPV3TRPV4PIK3CAPI4KB | |
| SCHEMBL25193000 | 0.71 | PDE10A (0.41) | CASP3TRPV3TRPV4PIK3CAPI4KB | |
| SCHEMBL5749124 | 0.70 | KMT2A (0.48) | TRPV3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902026-B1 | Herbicidal 2-azinyl-6-aryloxypyr(mi)dines | BASF AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| EP-0902026-A1 | Herbicidal 2-azinyl-6-aryloxypyr (mi) dines | American Cyanamid Company (US) | 1999-03-17 | — | — | EP | disclosed |