Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 7/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574691 | 1.00 | L3MBTL1 (0.40) | L3MBTL1ACLYCNR2MEN1KMT2A | |
| SCHEMBL574197 | 0.85 | ALDH1A1 (0.40) | L3MBTL1CNR2ALDH1A1KDM4ETSHR | |
| SCHEMBL574196 | 0.85 | ALDH1A1 (0.40) | L3MBTL1CNR2ALDH1A1KDM4ETSHR | |
| SCHEMBL10224228 | 0.84 | LMNA (0.39) | L3MBTL1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL572944 | 0.84 | LMNA (0.39) | L3MBTL1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL572943 | 0.84 | LMNA (0.39) | L3MBTL1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL10224224 | 0.83 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL572714 | 0.83 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL572715 | 0.83 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL573814 | 0.82 | LMNA (0.39) | L3MBTL1ALDH1A1KDM4ECYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598478-A2 | ARYLSULFONAMIDE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | Neurotherapeutics Pharma, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012018635-A2 | ARYLSULFONAMIDE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | NEUROTHERAPEUTICS PHARMA, INC. (US) | 2012-02-09 | — | — | WO | disclosed |