Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15428101 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4EPTPN1ERN1NFE2L2 | |
| SCHEMBL1605954 | 0.80 | HTR2A (0.41) | ALDH1A1KDM4EPTPN1ERN1NFE2L2 | |
| SCHEMBL22686914 | 0.78 | TDP1 (0.33) | TDP1MEN1KMT2ALMNATHRB | |
| SCHEMBL22687457 | 0.76 | TDP1 (0.55) | ALDH1A1PTPN1ERN1TDP1MEN1 | |
| SCHEMBL22687419 | 0.76 | MRGPRX4 (0.37) | ALDH1A1KDM4EPTPN1LMNASMN1; SMN2 | |
| SCHEMBL4363014 | 0.73 | ERN1 (0.46) | ALDH1A1KDM4EPTPN1ERN1NFE2L2 | |
| SCHEMBL29957006 | 0.73 | ERN1 (0.46) | ALDH1A1KDM4EPTPN1ERN1NFE2L2 | |
| SCHEMBL15428225 | 0.73 | CA12 (0.40) | ALDH1A1KDM4EPTPN1NFE2L2TDP1 | |
| SCHEMBL30134885 | 0.73 | CA12 (0.40) | ALDH1A1KDM4EPTPN1NFE2L2TDP1 | |
| SCHEMBL20482139 | 0.73 | KDM4E (0.37) | ALDH1A1KDM4EPTPN1ERN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289842-A1 | PHENYLDIHYDROPYRIMIDINE COMPOUND AND USE THEREOF | Hepagene Therapeutics (HK) Limited (HK) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022166923-A1 | PHENYLDIHYDROPYRIMIDINE COMPOUND AND USE THEREOF | 和博医药有限公司 | 2022-08-11 | — | — | WO | disclosed |
| US-10913770-B2 | Mertansine polypeptide conjugates | VISION GLOBAL HOLDINGS LIMITED (CN) | 2021-02-09 | — | — | US | disclosed |
| US-20200361988-A1 | MERTANSINE POLYPEPTIDE CONJUGATES | VISION GLOBAL HOLDINGS LIMITED (HK) | 2020-11-19 | — | — | US | disclosed |
| EP-2872590-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-11-14 | — | — | EP | disclosed |
| US-20060287529-A1 | Solid phase synthesis of antitumoral compounds | PHARMA MAR, S.A.U. (ES) | 2006-12-21 | — | — | US | disclosed |
| EP-1613635-A2 | SOLID PHASE SYNTHESIS OF ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004073598-A2 | SOLID PHASE SYNTHESIS OF ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A.U. (ES) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361988-A1 | MERTANSINE POLYPEPTIDE CONJUGATES | NGLY1, ANPEP, VIP | ALDH1A1 3769/4885KDM4E 3679/4885PTPN1 2608/4885 |
| US-10913770-B2 | Mertansine polypeptide conjugates | NGLY1, ANPEP, VIP | ALDH1A1 3769/4885KDM4E 3679/4885PTPN1 2608/4885 |
| US-20060287529-A1 | Solid phase synthesis of antitumoral compounds | TSNAX, TSN, PLIN5 | ALDH1A1 4682/4885KDM4E 2697/4885PTPN1 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.