Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552052 | 0.75 | ESR2 (0.44) | KDM4EPLAUALDH1A1HSD17B10HTT | |
| SCHEMBL407633 | 0.75 | CYP1A2 (0.55) | KDM4ELMNAALDH1A1MAPTKMT2A | |
| SCHEMBL206393 | 0.75 | BACE1 (0.47) | KDM4ELMNAALDH1A1MAPTHTT | |
| SCHEMBL208135 | 0.75 | BACE1 (0.47) | KDM4EALDH1A1MAPTHTTKMT2A | |
| SCHEMBL5750277 | 0.72 | LCK (0.44) | KDM4EPLAUALDH1A1HSD17B10ATM | |
| SCHEMBL5748489 | 0.71 | CYP1A2 (0.42) | KDM4ELMNAPOLBALDH1A1MAPT | |
| SCHEMBL5748279 | 0.71 | CYP2A6 (0.38) | KDM4EPOLBALDH1A1MAPTHSD17B10 | |
| SCHEMBL2302785 | 0.71 | SCN10A (0.39) | ALDH1A1MAPTHSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL315256 | 0.71 | NCF1 (0.51) | KDM4ELMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL407917 | 0.71 | BACE1 (0.51) | KDM4EKCNH2HRH3DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001096529-A2 | ACETYL GLUCOSAMINYL INOSITOL DEACETYLASE, A MYCOTHIOL BIOSYNTHETIC ENZYME, AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2001-12-20 | — | — | WO | claimed |
| EP-1252186-A2 | USE OF NEUREGULIN-BETA AS AN INDICATOR AND/OR TARGET | ProteoSys AG (DE) | 2002-10-30 | — | — | EP | disclosed |
| US-20020119938-A1 | Macrolide antiinfective agents | CHU DANIEL (US) | 2002-08-29 | — | — | US | disclosed |
| WO-2001058948-A2 | USE OF NEUREGULIN-β AS AN INDICATOR AND/OR TARGET | PROTEOSYS AG (DE) | 2001-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119938-A1 | Macrolide antiinfective agents | MLNR, DOHH, NOP2 | KDM4E 1780/4885LMNA 1595/4885POLB 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.