Biphenyl

Biphenyl

SCHEMBL8773175

CC(=O)OC(C)=O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.56
MAPT P10636 3/20 0.56
ALDH1A1 P00352 4/20 0.53
TSHR P16473 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.50
BACE1 P56817 1/20 0.47
GAA P10253 3/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
PKM P14618 1/20 0.45
CYP2C19 P33261 1/20 0.45
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
PTGS2 P35354 2/20 0.45
TDP1 Q9NUW8 3/20 0.43
PTGS1 P23219 2/20 0.43
ELANE P08246 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ESR1 P03372 1/20 0.43
ITGB3 P05106 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28823051 0.86 ALDH1A1 (0.62) SMN1; SMN2MAPTALDH1A1TSHRL3MBTL1
Biphenyl SCHEMBL29174568 0.84 MAPT (0.52) SMN1; SMN2MAPTALDH1A1TSHRL3MBTL1
Biphenyl SCHEMBL27819830 0.84 SMN1; SMN2 (0.56) SMN1; SMN2MAPTALDH1A1TSHRBACE1
Biphenyl SCHEMBL6269566 0.84 MAPT (0.56) SMN1; SMN2MAPTALDH1A1TSHRL3MBTL1
Biphenyl SCHEMBL29059196 0.83 SMN1; SMN2 (0.67) SMN1; SMN2MAPTALDH1A1TSHRL3MBTL1
Biphenyl SCHEMBL1822628 0.83 SMN1; SMN2 (0.67) SMN1; SMN2MAPTALDH1A1TSHRL3MBTL1
Biphenyl SCHEMBL15332958 0.83 SMN1; SMN2 (0.67) SMN1; SMN2MAPTALDH1A1TSHRL3MBTL1
Biphenyl SCHEMBL538359 0.83 SMN1; SMN2 (0.67) SMN1; SMN2MAPTALDH1A1TSHRL3MBTL1
Benzene SCHEMBL3128995 0.83 ALDH1A1 (0.77) MAPTALDH1A1TSHRGAAPTGS2
Toluene SCHEMBL2869833 0.82 LMNA (0.55) SMN1; SMN2MAPTALDH1A1TSHRPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978575-A Ageing-resistant emulsion and processing technology thereof 温州佳盛乳胶制品有限公司 2025-05-13 CN claimed
CN-113332496-A Preparation of composite scaffold material for vascular tissue engineering 杭州鹿扬科技有限公司 2021-09-03 CN claimed
CN-119978575-A Ageing-resistant emulsion and processing technology thereof 温州佳盛乳胶制品有限公司 2025-05-13 CN disclosed
CN-119978575-A Ageing-resistant emulsion and processing technology thereof 温州佳盛乳胶制品有限公司 2025-05-13 CN disclosed
CN-119039172-A N, N ', N ' ' -triacyl-1, 3, 5-tri (p-aminophenyl) benzene compound, preparation method and application 北京理工大学 2024-11-29 CN disclosed
CN-113332496-A Preparation of composite scaffold material for vascular tissue engineering 杭州鹿扬科技有限公司 2021-09-03 CN disclosed
EP-0439585-B1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS MAG GEORG MAYRHOFER & CO OHG (AT) 1997-10-29 EP disclosed
US-5610020-A CLEAVING TO LABEL MOLECULAR SPEICES IN ANALYTES; VOLATILE FOR DETERMINATION IN GAS PGHASE NORTHEASTERN UNIVERSITY (US) 1997-03-11 US disclosed
US-5604104-A BIOLOGICAL ANALYSIS USING A CLEAVABLE LABEL CAPABLE OF VOLATILIZATION AND DETECTION IN THE VAPOR PHASE; MEDICAL DIAGNOSIS; HUMAN GENOME PROJECT; GENETIC DISORDERS NORTHEASTERN UNIVERSITY (US) 1997-02-18 US disclosed
US-5602273-A WHEN CLEAVED RELEASE STABLE ELECTROPHORIC KETONES VOLATILE ENOUGH FOR DETERMINATION IN GAS PHASE NORTHEASTERN UNIVERSITY (US) 1997-02-11 US disclosed
US-5516931-A AROMATIC FLUORINATED KETONES FOR CHEMICAL LABELS NORTHEASTERN UNIVERSITY (US) 1996-05-14 US disclosed
US-5196478-A Polystyrene, assays EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1993-03-23 US disclosed
EP-0439585-A1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS. EPIPHARM ALLERGIE SERVICE (AT) 1991-08-07 EP disclosed
WO-1991002768-A1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1991-03-07 WO disclosed
US-4197395-A Crosslinking of mercaptan containing polymers with polyaldehyde compounds POLYSAR LIMITED (CA) 1980-04-08 US disclosed
US-4100137-A Crosslinking of hydroxyl-containing polymers with polyaldehyde compounds POLYSAR LIMITED (CA) 1978-07-11 US disclosed