Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5753279 | 0.93 | TRPA1 (0.42) | TRPA1AOC3LOXL2MMP2TAAR1 | |
| SCHEMBL5752240 | 0.92 | TRPA1 (0.49) | TRPA1AOC3TAAR1HTTIDO1 | |
| SCHEMBL5750053 | 0.89 | TRPA1 (0.39) | TRPA1TAAR1IDO1 | |
| SCHEMBL6578585 | 0.89 | TRPA1 (0.39) | TRPA1TAAR1IDO1 | |
| SCHEMBL5751727 | 0.89 | TRPA1 (0.39) | TRPA1TAAR1IDO1 | |
| SCHEMBL5752285 | 0.87 | CYP1A2 (0.55) | AOC3HTT | |
| SCHEMBL5751018 | 0.87 | MAOA (0.44) | TRPA1LOXL2 | |
| Hydrochloric Acid SCHEMBL5751082 | 0.87 | TACR1 (0.39) | TRPA1TAAR1IDO1 | |
| SCHEMBL5749784 | 0.86 | TRPA1 (0.41) | TRPA1AOC3MMP2 | |
| SCHEMBL5751556 | 0.85 | CASR (0.44) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | TRPA1 3461/4885AOC3 2703/4885LOXL2 2439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.