Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4868108 | 1.00 | ALDH1A1 (0.50) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Acetic Acid SCHEMBL29037898 | 1.00 | ALDH1A1 (0.50) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Acetic Acid SCHEMBL2354574 | 1.00 | ALDH1A1 (0.50) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Acetic Acid SCHEMBL10557658 | 0.97 | ALDH1A1 (0.47) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL44945 | 0.97 | — | — | |
| Tetrahydrofuran SCHEMBL1704980 | 0.97 | ALDH1A1 (0.53) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL28650393 | 0.97 | ALDH1A1 (0.53) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL7175965 | 0.94 | ALDH1A1 (0.50) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL7457134 | 0.94 | ALDH1A1 (0.50) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL7613346 | 0.94 | ALDH1A1 (0.50) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181137-A | Para-aryl substituted pyridinium derivative electrochromic material and preparation method thereof | 黎伟麒 | 2022-03-15 | — | — | CN | claimed |
| EP-3841141-B1 | A COMPOSITION, PREPARATION METHOD AND APPLICATION THEREOF | COVESTRO DEUTSCHLAND AG (DE) | 2025-01-01 | — | — | EP | disclosed |
| US-11965108-B2 | Composition, preparation method and application thereof | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2024-04-23 | — | — | US | disclosed |
| US-11965092-B2 | Polyurethane composition, preparation method and application thereof | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2024-04-23 | — | — | US | disclosed |
| EP-3841139-B1 | A POLYURETHANE COMPOSITION, PREPARATION METHOD AND APPLICATION THEREOF | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-10-04 | — | — | EP | disclosed |
| EP-3589677-B1 | A COMPOSITION, ITS PRODUCTION AND USE THEREOF | COVESTRO DEUTSCHLAND AG (DE) | 2023-04-12 | — | — | EP | disclosed |
| CN-115698179-A | Composition and preparation method and application thereof | 科思创德国股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-4058523-A1 | COMPOSITION, PREPARATION METHOD AND APPLICATION THEREOF | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-09-21 | — | — | EP | disclosed |
| CN-114829516-A | Composition and preparation method and application thereof | 科思创知识产权两合公司 | 2022-07-29 | — | — | CN | disclosed |
| EP-4026877-A1 | AN AQUEOUS COATING COMPOSITION AND A PREPARATION PROCESS THEREOF | Covestro Deutschland AG (DE) | 2022-07-13 | — | — | EP | disclosed |
| EP-2581374-B1 | Preparation of tetrahydropyrido[4,3-b]indole derivatives | INST PHARM & TOXICOLOGY AMMS (CN) | 2014-03-19 | — | — | EP | disclosed |
| US-20140030654-A1 | PHOTORESIST COMPOSITION AND METHOD FOR PRODUCING PHOTORESIST PATTERN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-30 | — | — | US | disclosed |
| EP-2417973-B1 | SUSTAINED RELEASE COMPOSITION CONTAINING TETRAHYDROPYRIDO [4, 3-B]INDOLE DERIVATIVE | INST PHARM & TOXICOLOGY AMMS (CN) | 2013-08-28 | — | — | EP | disclosed |
| EP-2581374-A1 | Preparation of tetrahydropyrido[4,3-b]indole derivatives | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China (CN) | 2013-04-17 | — | — | EP | disclosed |
| US-20120122914-A1 | Sustained-release composition containing tetrahydropyrido[4,3-b]indole derivatives and preparation of the derivatives | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCE P.L.A.CHINA (CN) | 2012-05-17 | — | — | US | disclosed |
| EP-2417973-A1 | SUSTAINED RELEASE COMPOSITION CONTAINING TETRAHYDROPYRIDO Ý4, 3-b¨INDOLE DERIVATIVE AND PREPARATION METHOD OF DERIVATIVE | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) | 2012-02-15 | — | — | EP | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| EP-1305293-A1 | HEXAHYDRO-7-IMINO-1H-AZEPIN-2-YL-HEXANOIC ACID DERIVATIVES AS INHIBITORS OF INDUCIBLE NITRIC OXIDE SYNTHASE | Pharmacia Corporation (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010139-A1 | HEXAHYDRO-7-1H-AZEPIN-2-YL-HAXANOIC ACID DERIVATIVES AS INHIBITORS OF INDUCIBLE NITRIC OXIDE SYNTHASE | PHARMACIA CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | ALDH1A1 1434/4885FFAR3 4271/4885LCK 3703/4885 |
| US-20120122914-A1 | Sustained-release composition containing tetrahydropyrido[4,3-b]indole derivatives and preparation of the derivatives | HTT, HTR5A, HTR3B | ALDH1A1 4161/4885FFAR3 1700/4885LCK 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.