Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | USP2 | O75604 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405502 | 0.90 | ALDH1A1 (0.62) | ALDH1A1USP2MEN1NPC1RAB9A | |
| SCHEMBL5633033 | 0.81 | USP2 (0.58) | ALDH1A1USP2MEN1NPC1RAB9A | |
| SCHEMBL3453313 | 0.81 | USP2 (0.55) | ALDH1A1USP2MEN1NPC1RAB9A | |
| Lithium Ion SCHEMBL5633232 | 0.80 | USP2 (0.57) | ALDH1A1USP2MEN1NPC1RAB9A | |
| SCHEMBL11201625 | 0.79 | USP2 (0.58) | ALDH1A1USP2MEN1NPC1RAB9A | |
| SCHEMBL12153235 | 0.79 | USP2 (0.58) | ALDH1A1USP2MEN1NPC1RAB9A | |
| SCHEMBL11101570 | 0.79 | USP2 (0.58) | ALDH1A1USP2MEN1NPC1RAB9A | |
| SCHEMBL27917816 | 0.78 | LMNA (0.72) | ALDH1A1USP2L3MBTL1MAPTLMNA | |
| SCHEMBL8253693 | 0.78 | USP2 (0.59) | ALDH1A1USP2MEN1NPC1RAB9A | |
| SCHEMBL13875589 | 0.78 | USP2 (0.63) | ALDH1A1USP2MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720872-A1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005090347-A1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |