Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | GALK1 | P51570 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14834301 | 0.84 | PKM (0.66) | LMNAALDH1A1PKMGALK1HTT | |
| SCHEMBL25802934 | 0.83 | PKM (0.64) | LMNAALDH1A1PKMGALK1HTT | |
| SCHEMBL2544136 | 0.79 | LMNA (0.56) | LMNAALDH1A1PKMGALK1HTT | |
| SCHEMBL5751254 | 0.78 | ALDH1A1 (0.70) | LMNAALDH1A1USP2NPSR1MAPT | |
| Hydrochloric Acid SCHEMBL5857416 | 0.78 | LMNA (0.55) | LMNAALDH1A1PKMGALK1HTT | |
| SCHEMBL2359491 | 0.76 | PKM (0.58) | LMNAALDH1A1PKMGALK1HTT | |
| SCHEMBL5858640 | 0.75 | ALDH1A1 (0.61) | LMNAALDH1A1PKMGALK1HTT | |
| SCHEMBL27849817 | 0.75 | PKM (0.56) | LMNAALDH1A1PKMGALK1HTT | |
| SCHEMBL5639465 | 0.73 | PKM (0.53) | LMNAALDH1A1PKMGALK1HTT | |
| SCHEMBL22587976 | 0.71 | HSD11B1 (0.62) | LMNAALDH1A1HTTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |