Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27623146 | 0.78 | GAA (0.50) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL6684769 | 0.78 | ATAD2 (0.50) | DPYDMAPTALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL28250779 | 0.77 | GAA (0.48) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL67366 | 0.67 | — | — | |
| SCHEMBL30727452 | 0.67 | PARP1 (0.50) | ALDH1A1LMNAPMP22SMN1; SMN2 | |
| SCHEMBL3282669 | 0.67 | PARP1 (0.50) | ALDH1A1LMNAPMP22SMN1; SMN2 | |
| SCHEMBL5801644 | 0.66 | ALDH1A1 (0.64) | DPYDMAPTALDH1A1LMNAGAA | |
| Water SCHEMBL27711509 | 0.65 | DPYD (0.50) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL6573722 | 0.64 | — | — | |
| SCHEMBL21930973 | 0.64 | DAO (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705045-B | Pyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2020-07-14 | — | — | CN | claimed |
| CN-108774218-B | Pyrimidine antitumor compound with 1,3, 4-oxadiazole structure and preparation method and application thereof | 中国医科大学 | 2020-04-21 | — | — | CN | claimed |
| CN-108794408-B | Pyrimidine phenylurea anti-tumor compound and preparation method and application thereof | 中国医科大学 | 2020-04-21 | — | — | CN | claimed |
| CN-109705045-A | Pyrimidine anti-tumor compounds and its preparation method and application | 中国医科大学 | 2019-05-03 | — | — | CN | claimed |
| CN-108794408-A | Pyrimidine phenylurea anti-tumor compounds and its preparation method and application | 中国医科大学 | 2018-11-13 | — | — | CN | claimed |
| CN-108774218-A | The pyrimidine anti-tumor compounds and its preparation method and application of 1,3,4- oxadiazoles structures | 中国医科大学 | 2018-11-09 | — | — | CN | claimed |
| US-20250115687-A1 | PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS | FORMOSA PLASTICS CORP USA (US) | 2025-04-10 | — | — | US | disclosed |
| WO-2025075722-A1 | PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2025-04-10 | — | — | WO | disclosed |
| CN-109705045-B | Pyrimidine antitumor compound and preparation method and application thereof | 中国医科大学 | 2020-07-14 | — | — | CN | disclosed |
| CN-108774218-B | Pyrimidine antitumor compound with 1,3, 4-oxadiazole structure and preparation method and application thereof | 中国医科大学 | 2020-04-21 | — | — | CN | disclosed |
| CN-108794408-B | Pyrimidine phenylurea anti-tumor compound and preparation method and application thereof | 中国医科大学 | 2020-04-21 | — | — | CN | disclosed |
| CN-109705045-A | Pyrimidine anti-tumor compounds and its preparation method and application | 中国医科大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-108794408-A | Pyrimidine phenylurea anti-tumor compounds and its preparation method and application | 中国医科大学 | 2018-11-13 | — | — | CN | disclosed |
| WO-2003079986-A2 | URACIL DERIVATIVES AS INHIBITORS OF TNF-ALPHA CONVERTING ENZYME (TACE) AND MATRIX METALLOPROTEINASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |
| WO-2003079986-A2 | URACIL DERIVATIVES AS INHIBITORS OF TNF-ALPHA CONVERTING ENZYME (TACE) AND MATRIX METALLOPROTEINASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |
| EP-1299361-A1 | PYRAZOLE DERIVATIVES | Pfizer Limited (GB) | 2003-04-09 | — | — | EP | disclosed |
| WO-2002004424-A9 | PYRAZOLE DERIVATIVES | PFIZER LTD (GB) | 2002-12-12 | — | — | WO | disclosed |
| US-20020032184-A1 | Pyrazole derivatives | PFIZER INC. | 2002-03-14 | — | — | US | disclosed |
| WO-2002004424-A1 | PYRAZOLE DERIVATIVES | PFIZER LIMITED (GB) | 2002-01-17 | — | — | WO | disclosed |
| US-3948901-A | Bis (2,4-dioxotetrahydropyrimidinyl-5-sulphonoamido) diphenylsulphoner | REZNIK VLADIMIR SAVICH | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032184-A1 | Pyrazole derivatives | POLRMT, TPMT, CYP3A43 | DPYD 6/4885MAPT 788/4885ALDH1A1 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.