Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.50 |
| ▸ | DPYD | Q12882 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751524 | 0.78 | DPYD (0.45) | ATAD2DPYDMAPTGAAALDH1A1 | |
| SCHEMBL27623146 | 0.78 | GAA (0.50) | ATAD2DPYDMAPTGAAALDH1A1 | |
| SCHEMBL3945548 | 0.78 | GAA (0.50) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL28250779 | 0.77 | GAA (0.48) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL8727441 | 0.68 | ATAD2 (0.79) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL17201833 | 0.67 | ATAD2 (1.00) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL750450 | 0.67 | ATAD2 (1.00) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL5235 | 0.67 | — | — | |
| Thymine SCHEMBL29669526 | 0.67 | — | — | |
| SCHEMBL5427704 | 0.66 | ATAD2 (0.41) | ATAD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450861-A2 | TARGETING NUCLEIC ACIDS TO A CELLULAR NUCLEUS | Mirus Corporation (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003012039-A2 | TARGETING NUCLEIC ACIDS TO A CELLULAR NUCLEUS | MIRUS CORPORATION (US) | 2003-02-13 | — | — | WO | disclosed |