Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751904 | 0.85 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2SLC27A1 | |
| SCHEMBL5751095 | 0.83 | SMO (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2SLC27A1 | |
| SCHEMBL21715166 | 0.81 | SMN1; SMN2 (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2SLC27A1 | |
| SCHEMBL31091138 | 0.81 | SMN1; SMN2 (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2SLC27A1 | |
| SCHEMBL5750395 | 0.80 | SMN1; SMN2 (0.50) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL22768015 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL5761581 | 0.76 | MGLL (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL1384337 | 0.75 | MGLL (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL1383740 | 0.75 | ALDH1A1 (0.46) | CYP1A2CYP2C19SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5758459 | 0.75 | MGLL (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651602-A2 | ARYL HETEROAROMATIC PRODUCTS, COMPOSITIONS COMPRISING THE SAME AND USE THEREOF | Aventis Pharma S.A. (FR) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005009947-A2 | ARYL HETEROAROMATIC PRODUCTS, COMPOSITIONS COMPRISING THE SAME AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2005-02-03 | — | — | WO | disclosed |
| US-20050020593-A1 | Aryl-heteroaromatic compounds, compositions comprising them and use | AVENTIS PHARMA (FR) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020593-A1 | Aryl-heteroaromatic compounds, compositions comprising them and use | TUBB3, TUBB, TUBB1 | CYP1A2 1664/4885CYP2C9 2724/4885CYP2C19 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.