Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.50 |
| ▸ | HTR2C | P28335 | 9/20 | 0.47 |
| ▸ | HTR1D | P28221 | 4/20 | 0.44 |
| ▸ | HTR1B | P28222 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752140 | 0.84 | HTR1A (0.71) | HTR1AHTR2CHTR1DHTR1B | |
| SCHEMBL11290643 | 0.72 | HTR1A (0.72) | HTR1AHTR1DHTR1B | |
| SCHEMBL6644029 | 0.71 | HTR1D (0.45) | HTR1AHTR1DHTR1B | |
| SCHEMBL5796580 | 0.71 | HTR1A (0.56) | HTR1AHTR2CHTR1DHTR1B | |
| SCHEMBL6640808 | 0.70 | HTR2A (0.73) | HTR1AHTR2CHTR1DHTR1BGPR84 | |
| SCHEMBL9456487 | 0.70 | HTR1D (0.74) | HTR1AHTR2CHTR1DHTR1B | |
| SCHEMBL10871259 | 0.69 | HTR2C (0.73) | HTR1AHTR2CHTR1DHTR1B | |
| SCHEMBL18932886 | 0.69 | HTR2A (0.71) | HTR1AHTR2CHTR1DHTR1B | |
| SCHEMBL733767 | 0.69 | MPO (0.71) | HTR1AGPR84 | |
| SCHEMBL31620029 | 0.69 | MPO (0.71) | HTR1AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1078928-A1 | Pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-02-28 | — | — | EP | disclosed |