Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.56 |
| ▸ | HTR2C | P28335 | 10/20 | 0.55 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752140 | 0.85 | HTR1A (0.71) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL8784258 | 0.73 | HTR1A (0.71) | HTR1AHTR2CHTR1DHTR1BADRA2C | |
| SCHEMBL8783632 | 0.72 | HTR1A (1.00) | HTR1AHTR2CHTR1DHTR1BADRA2C | |
| SCHEMBL8783763 | 0.71 | HTR1A (1.00) | HTR1AHTR2CHTR1DHTR1BADRA2C | |
| SCHEMBL7843588 | 0.71 | HTR1A (0.50) | HTR1AHTR2CHTR1DHTR1B | |
| SCHEMBL8784288 | 0.68 | HTR1A (0.64) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL8784514 | 0.68 | HTR1A (1.00) | HTR1AHTR2CHTR1DHTR1BADRA2C | |
| SCHEMBL8868836 | 0.68 | HTR1A (0.71) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL8899999 | 0.67 | HTR1A (0.67) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| Oxalic Acid SCHEMBL8900028 | 0.67 | HTR1A (0.88) | HTR1AHTR2CHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006053116-A2 | RIZATRIPTAN PROCESS | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-05-18 | — | — | WO | claimed |
| WO-2006053116-A2 | RIZATRIPTAN PROCESS | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-05-18 | — | — | WO | disclosed |