Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732863 | 0.77 | — | — | |
| SCHEMBL5753064 | 0.73 | HRH2 (0.39) | — | |
| SCHEMBL506554 | 0.70 | HTR2C (0.46) | — | |
| SCHEMBL507589 | 0.60 | GPR119 (0.42) | ALDH1A1MEN1MAPTMAPK1KMT2A | |
| SCHEMBL6192353 | 0.59 | MC4R (0.48) | — | |
| SCHEMBL30013156 | 0.58 | HRH2 (0.43) | ALDH1A1GAAMAPT | |
| SCHEMBL30509937 | 0.58 | PGR (0.43) | ALDH1A1MEN1GAAMAPTKMT2A | |
| SCHEMBL24379347 | 0.56 | ESR1 (0.51) | ALDH1A1RECQLMAPK1 | |
| SCHEMBL10306272 | 0.56 | MC4R (0.41) | ALDH1A1 | |
| SCHEMBL8274236 | 0.56 | FAAH (0.47) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |