Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EBP | Q15125 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8751246 | 0.84 | L3MBTL1 (0.61) | L3MBTL1EBPSIGMAR1 | |
| SCHEMBL10638033 | 0.84 | L3MBTL1 (0.42) | L3MBTL1EBPSIGMAR1 | |
| SCHEMBL10634290 | 0.83 | L3MBTL1 (0.44) | L3MBTL1EBPSIGMAR1 | |
| SCHEMBL10631498 | 0.83 | L3MBTL1 (0.44) | L3MBTL1EBPSIGMAR1ADRB2ADRB1 | |
| SCHEMBL10631515 | 0.81 | L3MBTL1 (0.42) | L3MBTL1EBPSIGMAR1CYP3A4 | |
| SCHEMBL7310593 | 0.80 | EBP (0.51) | L3MBTL1EBPSIGMAR1CYP3A4 | |
| SCHEMBL5752959 | 0.80 | EBP (0.51) | L3MBTL1EBPSIGMAR1CYP3A4 | |
| SCHEMBL7129611 | 0.80 | L3MBTL1 (0.43) | L3MBTL1EBPSIGMAR1 | |
| SCHEMBL7972441 | 0.79 | L3MBTL1 (0.51) | L3MBTL1EBPSIGMAR1CYP3A4 | |
| SCHEMBL5754384 | 0.77 | EBP (0.38) | L3MBTL1EBPSIGMAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1099692-B1 | N,N-SUBSTITUTED CYCLIC AMINE DERIVATIVES | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6737425-B1 | SUCH AS 1-((4-CYANO-5-METHYL-4-PHENYL)HEXYL)-4-(2-(4-FLUORO -PHENOXY)ETHYL)PIPERAZINE; NERVE SELECTIVE CALCIUM ANTAGONISTS | EISAI CO., LTD. (JP) | 2004-05-18 | — | — | US | disclosed |
| CN-1310709-A | N, N-substituted cyclic amine derivatives | EISAI CO LTD (JP) | 2001-08-29 | — | — | CN | disclosed |
| EP-1099692-A1 | N,N-SUBSTITUTED CYCLIC AMINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-05-16 | — | — | EP | disclosed |