Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.36 |
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7123235 | 0.86 | L3MBTL1 (0.43) | L3MBTL1EBPSIGMAR1ALDH1A1FFAR1 | |
| SCHEMBL7131088 | 0.84 | L3MBTL1 (0.43) | L3MBTL1EBPSIGMAR1ALDH1A1FFAR1 | |
| SCHEMBL7120022 | 0.84 | L3MBTL1 (0.43) | L3MBTL1EBPSIGMAR1CTSSCTSK | |
| SCHEMBL7128706 | 0.84 | L3MBTL1 (0.43) | L3MBTL1EBPSIGMAR1ALDH1A1FFAR1 | |
| SCHEMBL5751980 | 0.81 | EBP (0.51) | L3MBTL1EBPSIGMAR1CYP2C19HIF1A | |
| SCHEMBL5753392 | 0.80 | L3MBTL1 (0.44) | L3MBTL1EBPSIGMAR1 | |
| SCHEMBL8359862 | 0.79 | KCNN4 (0.41) | KCNN4CYP2C19MEN1ALDH1A1KMT2A | |
| SCHEMBL7972441 | 0.78 | L3MBTL1 (0.51) | L3MBTL1EBPSIGMAR1CYP2C19MEN1 | |
| SCHEMBL7126244 | 0.78 | EBP (0.40) | KCNN4EBPSIGMAR1CTSSCTSK | |
| SCHEMBL7956093 | 0.77 | L3MBTL1 (0.40) | L3MBTL1EBPSIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667412-B1 | Carboxylic acid, ester or alcohol derivatives; n,n-substi-tuted cyclic amine or phenylacetonitrile intermediates; low cost; stability, workability, final product purity | EISAI CO., LTD. (JP) | 2003-12-23 | — | — | US | claimed |
| EP-1167348-A1 | NITRILE DERIVATIVES | Eisai Co., Ltd. (JP) | 2002-01-02 | — | — | EP | claimed |
| US-6667412-B1 | Carboxylic acid, ester or alcohol derivatives; n,n-substi-tuted cyclic amine or phenylacetonitrile intermediates; low cost; stability, workability, final product purity | EISAI CO., LTD. (JP) | 2003-12-23 | — | — | US | disclosed |
| EP-1167348-A1 | NITRILE DERIVATIVES | Eisai Co., Ltd. (JP) | 2002-01-02 | — | — | EP | disclosed |