Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755403 | 0.94 | CACNA1B (0.40) | CACNA1BHSD17B10SRCACKR3ATM | |
| SCHEMBL5754912 | 0.89 | CACNA1B (0.43) | ALDH1A1CACNA1BTP53P2RX7HSD17B10 | |
| SCHEMBL5758645 | 0.89 | CACNA1B (0.43) | ALDH1A1CACNA1BTP53P2RX7HSD17B10 | |
| SCHEMBL5756749 | 0.85 | POLB (0.41) | ALDH1A1CACNA1BP2RX7KMT2APOLB | |
| SCHEMBL5755981 | 0.84 | KMT2A (0.38) | ALDH1A1CACNA1BTP53P2RX7HSD17B10 | |
| SCHEMBL5757036 | 0.83 | CACNA1B (0.45) | ALDH1A1CACNA1BP2RX7HSD17B10KMT2A | |
| SCHEMBL5759035 | 0.83 | CACNA1B (0.49) | CACNA1BHSD17B10ACKR3ATMMEN1 | |
| SCHEMBL5754117 | 0.82 | CACNA1B (0.42) | ALDH1A1CACNA1BLMNASRCATM | |
| SCHEMBL5755535 | 0.82 | MEN1 (0.36) | ALDH1A1CACNA1BTP53P2RX7LMNA | |
| SCHEMBL5753729 | 0.82 | ALDH1A1 (0.36) | ALDH1A1CACNA1BP2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |