Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | YAP1 | P46937 | 3/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754183 | 0.94 | ALDH1A1 (0.35) | CACNA1BHSD17B10ACKR3ATMSRC | |
| SCHEMBL5759035 | 0.89 | CACNA1B (0.49) | CACNA1BHSD17B10ACKR3ATMGHSR | |
| SCHEMBL5753527 | 0.84 | NPC1 (0.39) | CACNA1BKDM4E | |
| SCHEMBL5754795 | 0.84 | CACNA1B (0.43) | CACNA1BHSD17B10ACKR3ATMGHSR | |
| SCHEMBL5754577 | 0.83 | REN (0.39) | ATM | |
| SCHEMBL5754912 | 0.83 | CACNA1B (0.43) | CACNA1BHSD17B10ATMYAP1SRC | |
| SCHEMBL5758645 | 0.83 | CACNA1B (0.43) | CACNA1BHSD17B10ATMYAP1SRC | |
| SCHEMBL5754438 | 0.83 | CACNA1B (0.51) | CACNA1BHSD17B10ATM | |
| SCHEMBL5758199 | 0.82 | CACNA1B (0.43) | CACNA1BHSD17B10ATMGHSRYAP1 | |
| SCHEMBL5754702 | 0.81 | CACNA1B (0.34) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |