Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.31 |
| ▸ | USP21 | Q9UK80 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | CCR3 | P51677 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5753443 | 0.88 | GSK3B (0.33) | L3MBTL1EPHX1CACNA1GKDM4ELMNA | |
| SCHEMBL5755568 | 0.85 | CACNA1B (0.35) | L3MBTL1EPHX1KDM4ELMNAMAPT | |
| SCHEMBL5755092 | 0.84 | EPHX1 (0.32) | L3MBTL1EPHX1KDM4ELMNAMAPT | |
| SCHEMBL5757142 | 0.82 | ALDH1A1 (0.42) | L3MBTL1EPHX1MAPTHTTALDH1A1 | |
| SCHEMBL5756658 | 0.80 | CACNA1B (0.39) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL5755160 | 0.80 | EPHX1 (0.33) | L3MBTL1EPHX1KDM4ELMNAMAPT | |
| SCHEMBL5756516 | 0.79 | CCR3 (0.34) | L3MBTL1EPHX1KDM4ELMNAMAPT | |
| SCHEMBL5759489 | 0.79 | MCL1 (0.34) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL5754339 | 0.78 | ALDH1A1 (0.35) | ALDH1A1KMT2A | |
| SCHEMBL5752525 | 0.78 | BACE1 (0.32) | L3MBTL1KDM4ELMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |