Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754826 | 0.80 | PPARA (0.48) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL177445 | 0.79 | THRA (0.47) | ALDH1A1HSD17B10RARBTHRATHRB | |
| SCHEMBL1007329 | 0.77 | MT-CO2 (0.51) | ALDH1A1POLB | |
| SCHEMBL1008034 | 0.77 | MT-CO2 (0.39) | HPGDALDH1A1RAB9AKDM4E | |
| SCHEMBL3332104 | 0.76 | HPGD (0.43) | HPGDALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL5756917 | 0.75 | HDAC3 (0.37) | THRATHRBHDAC3HDAC1HDAC2 | |
| SCHEMBL7112682 | 0.75 | KCNH2 (0.41) | ALDH1A1RARBTHRATHRBFAAH | |
| SCHEMBL3339006 | 0.74 | HPGD (0.41) | HPGDALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL6404151 | 0.72 | CYP4A11 (0.46) | HPGDALDH1A1HSD17B10CA2 | |
| SCHEMBL6405545 | 0.72 | CYP4Z1 (0.41) | HPGDALDH1A1HSD17B10THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | disclosed |