SCHEMBL6404151

SCHEMBL6404151

CCOC(=O)N(Br)c1ccc(CCCO)cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP4A11 Q02928 5/20 0.46
CYP4F2 P78329 4/20 0.46
PPARA Q07869 1/20 0.41
CYP4Z1 Q86W10 2/20 0.39
CYP4F11 Q9HBI6 1/20 0.39
CYP4F12 Q9HCS2 1/20 0.39
CA2 P00918 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
ALOX5 P09917 2/20 0.36
LMNA P02545 1/20 0.36
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LTA4H P09960 1/20 0.35
EPHX2 P34913 1/20 0.35
GLA P06280 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6406595 0.96 CYP4A11 (0.47) CYP4A11CYP4F2PPARACYP4Z1CYP4F11
SCHEMBL6405545 0.88 CYP4Z1 (0.41) CYP4A11CYP4F2CYP4Z1CYP4F11CYP4F12
SCHEMBL6554455 0.87 THRA (0.43) CYP4A11CYP4F2CYP4Z1CYP4F11CYP4F12
SCHEMBL6554503 0.78 CYP4A11 (0.45) CYP4A11CYP4F2PPARACA2ALOX5
SCHEMBL9869627 0.76 ALDH1A1 (0.50) CTDSP1LMNAALDH1A1HPGDHSD17B10
SCHEMBL8866817 0.74 CYP4F2 (0.57) CYP4A11CYP4F2PPARACA2CTDSP1
SCHEMBL3049924 0.73 CYP4A11 (0.70) CYP4A11CYP4F2CA2LMNAALDH1A1
SCHEMBL5755875 0.72 HPGD (0.44) CA2ALDH1A1HPGDHSD17B10
SCHEMBL9495382 0.71 IGF1R (0.46) CYP4A11CYP4F2PPARACA2LTA4H
SCHEMBL26295423 0.71 IGF1R (0.46) CYP4A11CYP4F2PPARACA2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050171101-A1 Phenanthridinones as parp inhibitors FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2005-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050171101-A1 Phenanthridinones as parp inhibitors PARP1, PARP11, PARP2 CYP4A11 2762/4885CYP4F2 3749/4885PPARA 3832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.