Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746374 | 1.00 | IDO1 (0.36) | IDO1P2RX7TBXAS1PIK3CD | |
| SCHEMBL16160188 | 0.92 | IDO1 (0.36) | IDO1P2RX7TBXAS1 | |
| SCHEMBL16160200 | 0.92 | IDO1 (0.36) | IDO1P2RX7TBXAS1 | |
| SCHEMBL16160948 | 0.86 | SPHK1 (0.38) | IDO1P2RX7 | |
| SCHEMBL16160950 | 0.86 | SPHK1 (0.38) | IDO1P2RX7 | |
| SCHEMBL5758196 | 0.83 | — | — | |
| SCHEMBL5756848 | 0.83 | — | — | |
| SCHEMBL5758333 | 0.81 | P2RX7 (0.33) | P2RX7TBXAS1 | |
| SCHEMBL6746347 | 0.80 | CYP1A2 (0.30) | — | |
| SCHEMBL6746322 | 0.80 | CYP1A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562920-B1 | ANTIINFLAMMATORY 3-ARYLTHIO-3-THIAZOLYL-ALKYLAMINES | ASTRAZENECA AB (SE) | 2006-06-28 | — | — | EP | disclosed |
| US-20060040992-A1 | Antiinflammatory 3-arylthio-3-thiazolyl-alkylamines | ASTRAZENECA AB (SE) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040992-A1 | Antiinflammatory 3-arylthio-3-thiazolyl-alkylamines | NOS3, PTGIS, PTGES3 | IDO1 87/4885P2RX7 230/4885TBXAS1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.