Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16160174 | 0.94 | P2RX7 (0.33) | P2RX7TBXAS1 | |
| SCHEMBL16160965 | 0.89 | BRD4 (0.34) | P2RX7 | |
| SCHEMBL6746218 | 0.84 | CYP2D6 (0.33) | — | |
| SCHEMBL4595234 | 0.84 | CYP2D6 (0.33) | — | |
| SCHEMBL6232927 | 0.84 | CYP2D6 (0.33) | — | |
| SCHEMBL6746223 | 0.84 | CYP2D6 (0.33) | — | |
| SCHEMBL6752549 | 0.83 | ITGB3 (0.37) | — | |
| SCHEMBL6746374 | 0.81 | IDO1 (0.36) | P2RX7TBXAS1 | |
| SCHEMBL5757217 | 0.81 | IDO1 (0.36) | P2RX7TBXAS1 | |
| SCHEMBL5758835 | 0.76 | CYP2D6 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562920-B1 | ANTIINFLAMMATORY 3-ARYLTHIO-3-THIAZOLYL-ALKYLAMINES | ASTRAZENECA AB (SE) | 2006-06-28 | — | — | EP | disclosed |
| US-20060040992-A1 | Antiinflammatory 3-arylthio-3-thiazolyl-alkylamines | ASTRAZENECA AB (SE) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040992-A1 | Antiinflammatory 3-arylthio-3-thiazolyl-alkylamines | NOS3, PTGIS, PTGES3 | P2RX7 230/4885TBXAS1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.