Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 5/20 | 0.62 |
| ▸ | PRKACA | P17612 | 8/20 | 0.58 |
| ▸ | PRKACG | P22612 | 8/20 | 0.58 |
| ▸ | PRKACB | P22694 | 8/20 | 0.58 |
| ▸ | PRKCB | P05771 | 7/20 | 0.50 |
| ▸ | PRKCG | P05129 | 6/20 | 0.50 |
| ▸ | PRKCA | P17252 | 6/20 | 0.50 |
| ▸ | GSK3B | P49841 | 6/20 | 0.50 |
| ▸ | CDK4 | P11802 | 5/20 | 0.50 |
| ▸ | CCND1 | P24385 | 5/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | PIM1 | P11309 | 3/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.50 |
| ▸ | CDK1 | P06493 | 2/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.50 |
| ▸ | PRKCH | P24723 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757611 | 0.84 | GSK3B (0.59) | PRKACAPRKACGPRKACBPRKCBPRKCG | |
| SCHEMBL9085908 | 0.83 | PRKACA (0.80) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL5756779 | 0.82 | CAMK2D (0.77) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL5756702 | 0.81 | GSK3B (0.71) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL9087699 | 0.79 | PRKACA (0.65) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL9084329 | 0.79 | PRKACA (0.65) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL9086911 | 0.78 | PRKACA (0.64) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL9086168 | 0.78 | PRKACA (0.63) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL9088633 | 0.78 | PRKACA (0.63) | CAMK2DPRKACAPRKACGPRKACBPRKCB | |
| SCHEMBL9085285 | 0.78 | PRKACA (0.63) | CAMK2DPRKACAPRKACGPRKACBPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362047-B1 | INDAZOLYL-SUBSTITUTED PYRROLINE COMPOUNDS AS KINASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2006-05-17 | — | — | EP | disclosed |