Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645803 | 0.95 | FAAH (0.49) | EPHX2FAAHALDH1A1KDM4EHPGD | |
| SCHEMBL2644339 | 0.79 | KEAP1 (0.46) | EPHX2ALDH1A1HPGDPOLBL3MBTL1 | |
| SCHEMBL2768877 | 0.77 | TSHR (0.48) | ALDH1A1MEN1KMT2AEPHX1 | |
| SCHEMBL800064 | 0.75 | EPHX2 (0.56) | EPHX2FAAHALDH1A1KDM4EHPGD | |
| SCHEMBL3553273 | 0.75 | FAAH (0.42) | EPHX2FAAHALDH1A1KDM4EHPGD | |
| SCHEMBL1624945 | 0.75 | MCL1 (0.49) | ALDH1A1POLBEPHX1 | |
| SCHEMBL163232 | 0.74 | EPHX2 (0.59) | EPHX2FAAHALDH1A1KDM4EHPGD | |
| SCHEMBL5160492 | 0.72 | TSHR (0.49) | ALDH1A1KMT2AL3MBTL1EPHX1 | |
| SCHEMBL2078210 | 0.72 | TSHR (0.49) | ALDH1A1KMT2AL3MBTL1EPHX1 | |
| SCHEMBL4656202 | 0.72 | ALDH1A1 (0.56) | EPHX2FAAHALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | disclosed |