Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | TACR1 | P25103 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758376 | 0.86 | SIGMAR1 (0.49) | SIGMAR1TACR1CNR1CNR2CCR3 | |
| SCHEMBL5754847 | 0.80 | EPHX2 (0.53) | CCR3MEN1KMT2A | |
| SCHEMBL6008659 | 0.78 | KCNH2 (0.53) | SIGMAR1KCNH2MEN1KMT2AS1PR5 | |
| SCHEMBL5758045 | 0.76 | HTR2A (0.44) | KCNH2CCR3MEN1KMT2A | |
| SCHEMBL5327611 | 0.73 | CNR1 (0.57) | SIGMAR1CNR1CNR2CA1CA2 | |
| SCHEMBL5757058 | 0.72 | SLC18A3 (0.47) | CCR3CCR5 | |
| Hydrochloric Acid SCHEMBL5755104 | 0.72 | HTR2A (0.47) | KCNH2CCR3MEN1KMT2A | |
| SCHEMBL5753993 | 0.71 | KMT2A (0.46) | SIGMAR1CNR1CNR2KMT2ACCR5 | |
| SCHEMBL5756913 | 0.70 | CYP2C19 (0.51) | — | |
| SCHEMBL6009253 | 0.68 | KCNH2 (0.55) | SIGMAR1KCNH2MEN1KMT2AS1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | claimed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | claimed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | claimed |