Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007927 | 0.91 | KCNH2 (0.57) | KCNH2S1PR5MEN1KMT2AHTR2A | |
| SCHEMBL6007910 | 0.89 | KCNH2 (0.50) | KCNH2S1PR5HTR2ASIGMAR1CHRM2 | |
| SCHEMBL6007909 | 0.88 | MGLL (0.54) | KCNH2MEN1KMT2AHTR2AMGLL | |
| SCHEMBL6007356 | 0.86 | HTR2A (0.61) | KCNH2MEN1KMT2AHTR2AKDM4E | |
| SCHEMBL6009354 | 0.85 | KCNH2 (0.61) | KCNH2S1PR5MEN1KMT2AKDM4E | |
| SCHEMBL6009245 | 0.83 | MGLL (0.54) | KCNH2MEN1KMT2AHTR2AMGLL | |
| SCHEMBL6009242 | 0.80 | MEN1 (0.57) | KCNH2MEN1KMT2AHTR2A | |
| SCHEMBL6009428 | 0.80 | ALDH1A1 (0.53) | MEN1KMT2ASIGMAR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6007421 | 0.79 | ALDH1A1 (0.52) | MEN1KMT2ASIGMAR1KDM4EALDH1A1 | |
| SCHEMBL3838687 | 0.79 | HTR2A (0.61) | HTR2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | claimed |
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |