Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 10/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31221972 | 0.92 | HTR7 (0.55) | HTR7HRH3SIGMAR1 | |
| SCHEMBL11144109 | 0.90 | SIGMAR1 (0.57) | HTR7HRH3SIGMAR1 | |
| SCHEMBL4928468 | 0.88 | SIGMAR1 (0.58) | HTR7HRH3SIGMAR1 | |
| SCHEMBL13305330 | 0.83 | SIGMAR1 (0.56) | HTR7HRH3SIGMAR1 | |
| SCHEMBL7391446 | 0.80 | HTR7 (0.55) | HTR7 | |
| SCHEMBL7384667 | 0.80 | HTR7 (0.55) | HTR7 | |
| SCHEMBL5757906 | 0.78 | KCNH2 (0.63) | HRH3SIGMAR1 | |
| SCHEMBL13305348 | 0.78 | SIGMAR1 (0.56) | HTR7HRH3SIGMAR1 | |
| SCHEMBL2353465 | 0.78 | SIGMAR1 (0.59) | HRH3SIGMAR1BCHEACHE | |
| SCHEMBL5757125 | 0.76 | SIGMAR1 (0.46) | HRH3SIGMAR1ADRA2AADRA2CDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | claimed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | claimed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | claimed |
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | disclosed |