SCHEMBL7384667

SCHEMBL7384667

CN(CCCCCCN1CC[CH]CC1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 12/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7391446 1.00 HTR7 (0.55) HTR7
Bromide SCHEMBL31221972 0.85 HTR7 (0.55) HTR7
SCHEMBL7391864 0.81 SIGMAR1 (0.58)
SCHEMBL5759101 0.80 HTR7 (0.56) HTR7
SCHEMBL7392437 0.79 MAOB (0.56)
SCHEMBL17037834 0.78 SIGMAR1 (0.52) HTR7
SCHEMBL7394145 0.77 ALDH1A1 (0.44)
SCHEMBL13645984 0.76 SIGMAR1 (0.48) HTR7
SCHEMBL7383012 0.75 BCHE (0.59)
SCHEMBL7386124 0.75 BCHE (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5864039-A THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1999-01-26 US disclosed
EP-0873990-A1 BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1998-10-28 EP disclosed