Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.71 |
| ▸ | QPCT | Q16769 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759785 | 0.91 | HMOX1 (0.85) | HMOX1QPCTLTA4HKMT2ACYP19A1 | |
| SCHEMBL5757778 | 0.87 | HMOX1 (0.83) | HMOX1QPCTLTA4HKMT2ACYP19A1 | |
| SCHEMBL5760109 | 0.79 | HMOX1 (0.65) | HMOX1QPCTKMT2ACYP19A1TBXAS1 | |
| SCHEMBL3160306 | 0.78 | CYP19A1 (0.71) | HMOX1QPCTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL5759974 | 0.77 | HMOX1 (0.62) | HMOX1QPCTLTA4HKMT2ACYP19A1 | |
| SCHEMBL5761690 | 0.77 | HMOX1 (0.56) | HMOX1QPCTLTA4HKMT2A | |
| Hydrochloric Acid SCHEMBL411704 | 0.77 | CYP19A1 (0.69) | HMOX1QPCTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL5759151 | 0.76 | HMOX1 (0.64) | HMOX1QPCTKMT2ACYP19A1 | |
| SCHEMBL7477480 | 0.76 | HMOX1 (0.75) | HMOX1QPCTLTA4HKMT2ACYP19A1 | |
| SCHEMBL5760287 | 0.75 | CYP11B1 (0.59) | HMOX1KMT2ACYP19A1CYP11B1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |